Restless Souls/Technology: Difference between revisions

===Explanation attempt of the biological dimension===

| '''to put it into a nutshell'''<br>[http://i305.photobucket.com/albums/nn207/unknownfuture/Oni_Galore_Images/RS_technology/Daodan-Chrysalis_2012_in_a_nutshell_small.png http://i305.photobucket.com/albums/nn207/unknownfuture/Oni_Galore_Images/RS_technology/Daodan-Chrysalis_2012_in_a_nutshell_tn.png]

The Daodan Chrysalis (short: Daodan) produces always mutations that are really needed. Only that way the same damage source won't be dangerous again in the future.

Thus the type of damage becomes analyzed and therefore the Daodan requires a sensor system.

In nature, "higher lifeforms" evolved by following – among other concepts – specialization and socialization. Those find their expression on one hand in different cell types – therefore multicellular organism – and on other hand in all kinds of symbiosis. So, for a hyperevolved organism, it wound be understandable if it work more intensely by those concepts.

A body realizes damage or harmful influences by stimuli. To detect all kind of stimuli, much space is surely needed.

Ninety percent of cells that can be found on and inside the human body aren't his own but microorganisms. Fortunately they weigh only a half up to one kilogram. Their assemblage is known as human flora. Depending on the organism, one of them can be a ''[[wikipedia:Squatting|squatter]]'' (in metaphorical sense) against real health threatening germs or another one can hold an actual ability like [[wikipedia:Vitamin_K|vitamin K production]].

Some abilities can't be simply or sufficiently integrated into an organism but its product can be received from a symbiont.

So, it seems likely to enlist microorganisms for more sensory tasks and abilities which are actually alien to the human. For this reason the Daodan needs to upgrade the genomes of all the microorganisms [[wikipedia:Microbiome|(microbiome)]] as well.

Next, communication between the symbionts has to be ensured. A new cell organelle might do the job by using messenger substances. Or it transmits different electromagnetic waves which existence doesn't seem too alien in comparison to the real bioelectric field of each living organism and wound give an explanation attempt of the Daodan glow. (Some metabolic waste products – which are released through the body surface together with perspiration – might become stimulated to glow by the field.)

For processing the received information, the Daodan might use an own ''self-awareness'', mainly a (genetic and) anatomic model of itself formed by another organelle type inside every daodanized cell. The presence of such organelle in neurons opens the possibility for – how geyser coined it –  “schizophrenia of the 3rd kind” but also Kerr's idea of a mental interface which allows influence on the Daodan's development by the host's personality.

If we want to know more about the decision making algorithms (and their physical structures) which calculates the mutations, we will need to ask Hasegawa. ;-)

Depending on the target – human Daodan genome, Daodan microbiome, both their epigenomes, or even organelle genomes (like mitochondrions and plastids have) – a few different “vectors” (e.g. viruses) need to be available to transport the mutation. (To ease further talk one might like to fall back on the terms holobiont, sum of symbionts, and hologenom, sum of symbionts' genomes.)

However, it's hard to believe that the Daodan could be able to come up with fitting mutations completely by its own. It seems more likely to me that it draws on “genetic building blocks” holding basis information for fast regeneration, resistances, different metabolisms, and so on. Maybe the Daodan can also make use of already existing genetic material of the microbes: after all, a human just has 23 000 genes (500 000 up to 1 000 000 proteins through alternative splicing) while his microbiome has more than [http://www.hsph.harvard.edu/news/press-releases/2012-releases/human-microbiome-project.html 5 million] genes/proteins.

The microbiome is very different among humans and would make the Daodan mass production surly no easy task. But after more than 15 years the Syndicate should have accomplished a way to simplify the process. This second generation would be independent from the host's sex (XX / YX chromosomes) and the microbiom's composition by providing level-zero stem cells. These can target any compatible symbiont cell and then do a “configuration” (whereby they dissolve the unnecessary genetic material) to become ''classic'' daodanized stem cells and microbes.

Daodan 3. generation: adds enhenced degradosome ?

====Arguments of an ''in vitro Daodan''====

: If the Daodan project was intended as tool to cure human cells in glass tubes, minimization could lead to portable devices used in cases of emergency.

: Probably you would insert a few cells to daodanize and replicate them. Expose it afterwards to doses of negative stimuli such as toxins and grow adapted tissue or organs. Before transplanting the daodanized cells, their ability to adapt and hyperregenerate would be turned off. Then it would be like bioprinting (a.k.a. [[wikipedia:Tissue_engineering|tissue engineering]]) with normal cells.

: However, the question remains why Konoko's and Muro's DNA was taken for the prototypes.

:* During life, mutations accumulate inside the genetic and epigenetic code. The codes of children is less mutated, hence need less repair, also the telomeres are longer.

:* If Hasegawa and Kerr repetitively needs new samples they would have Muro and Mai as source without asking anyone else from the outside.

:Although there are points to backup an "in vitro" scenario, the WCG could easily spread doubts about such a Daodan to an audience which lacks the technical background which would be pretty much everyone.

====Arguments of an ''in vivo Daodan''====

A "Box-Daodan" could never get influenced by someone's personality.

So for an accurate regeneration of the complex human body the Daodan needs an own ''self-awareness'', mainly a genetic and anatomic model of itself, as already written in the [[#Explanation attempt of the biological dimension|explanation attempt]] section. The processing cell organelles in neurons open a little door so that the Doadan can get influenced. This might be the reason for Kerr's "wishful thinking".

The only way Hasegawa and Kerr could have discovered this possible side effect, is an entire brain simulation with Daodan cells.

Speaking of injuries, also the brain can get injured and these can not only be life threatening but also alter the way someone feel, remember and think. Kerr and Co. could have run simulations to see how well the tissues grow together again. In doing so they might have accidentally discovered circumstances where the neuronal activities led to novel interactions with the Daodan organelles.

All in all, due to the complexity of the Daodan, Kerr's could say that they needed at least one male and one female prototype tested in vivo before they could create a mass-produced version of an in vitro Daodan.