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** Here comes [[wikipedia:Transdifferentiation|transdifferentiation]] very handy, this process changes the cell type directly. | ** Here comes [[wikipedia:Transdifferentiation|transdifferentiation]] very handy, this process changes the cell type directly. | ||
* In 2013 another [ | * In 2013 another [https://www.sciencedaily.com/releases/2013/01/130110121020.htm direct cell type conversion] was demonstrated whereby only one type of protein needed to get repressed. That's good news because methods based on viral vectors, plasmids and RNA can alter the genome in an unintentional way or have other problematic side effects. | ||
* In 2017 [https://phys.org/news/2017-06-two-part-stem-cells.html control of plasmids] (ring-shaped bacterial genomes) has been improved. With it normal stem cells have been reliable differentiated. As soon as this can be achieved with iPSC, tissue engineering should get a boost resulting in myriads of applications. For unhealable diseases you can expect that they will cut out the tissue and replace it with a printed chunk. | * In 2017 [https://phys.org/news/2017-06-two-part-stem-cells.html control of plasmids] (ring-shaped bacterial genomes) has been improved. With it normal stem cells have been reliable differentiated. As soon as this can be achieved with iPSC, tissue engineering should get a boost resulting in myriads of applications. For unhealable diseases you can expect that they will cut out the tissue and replace it with a printed chunk. |