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Bertram Navarre: Difference between revisions
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===Reality soon outruns fiction ?=== | |||
* Retasking a cell is also known as transdifferentiation whereby the cell type becomes directly changed. | * Retasking a cell is also known as transdifferentiation whereby the cell type becomes directly changed. | ||
** In nature, cells usually ''do one step backwards'' ([http://en.wikipedia.org/wiki/Cellular_differentiation#Dedifferentiation dedifferentiation]) before they transform into a new cell type (redifferentiation). | ** In nature, cells usually ''do one step backwards'' ([http://en.wikipedia.org/wiki/Cellular_differentiation#Dedifferentiation dedifferentiation]) before they transform into a new cell type (redifferentiation). | ||
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* Due to ethical concerns scientists looked for an alternative way to gain human pluripotent cells. Some people argue that separating human embryonic stem cells is equal to a kill: to them it matters the cells' potential to become a complete human. Other people don't have concerns about this because the embryonic stem cells would be separated before neurons and a possible personality form. -- With the new methods, mature cells become reprogrammed to so-called [[wikipedia:Induced_pluripotent_stem_cells|induced pluripotent stem cells (iPSC)]]. Those cells - which are very similar to ESC - can then be prompted to differentiate again into the desired cell types. | * Due to ethical concerns scientists looked for an alternative way to gain human pluripotent cells. Some people argue that separating human embryonic stem cells is equal to a kill: to them it matters the cells' potential to become a complete human. Other people don't have concerns about this because the embryonic stem cells would be separated before neurons and a possible personality form. -- With the new methods, mature cells become reprogrammed to so-called [[wikipedia:Induced_pluripotent_stem_cells|induced pluripotent stem cells (iPSC)]]. Those cells - which are very similar to ESC - can then be prompted to differentiate again into the desired cell types. | ||
** In 2012 a mouse spine was [http://www.ncbi.nlm.nih.gov/pubmed/22223498 repaired] with iPSC | ** In 2012 a mouse spine was [http://www.ncbi.nlm.nih.gov/pubmed/22223498 repaired] with iPSC. | ||
* In 2013 [http://www.sciencedaily.com/releases/2013/01/130110121020.htm direct cell type conversion] has been demonstrated and this even without viral vectors. | |||
** So for the year 2032 it seems totally possible to regenerate spinal damages in humans. With that in mind, Bertram Navarre depicts a very believable speculation about future's technology. | |||