Bertram Navarre: Difference between revisions

Bertram Navarre (view source)

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+==Added value==
+* Retasking a cell is also known as transdifferentiation whereby the cell type becomes directly changed.
+** In nature, cells usually ''do one step backwards'' ([http://en.wikipedia.org/wiki/Cellular_differentiation#Dedifferentiation dedifferentiation]) before they transform into a new cell type (redifferentiation).
+* At first scientists tried to repair nerve damages by taking [[wikipedia:Embryonic_stem_cell|embryonic stem cells (ESC)]] and let them replicate and then specialize to nerve cells.
+** In 1999 a mouse spine was [http://www.nature.com/nm/journal/v5/n12/abs/nm1299_1410.html repaired] with ESC to some degree. -- At that time Oni's story was rewritten. It might be possible that Hardy read about the experiment and pushed the idea a few steps further.
+* Due to ethical concerns scientists looked for an alternative way to gain human pluripotent cells. Some people have the standpoint that separating human embryonic stem cells is equal to a kill: to them it matters the cells' potential to become a complete human. Other people don't have concerns about this because the embryonic stem cells would be separated before neurons and a possible personality form. -- With the new methods specialized cells can become reprogrammed so that they transform back into [[wikipedia:Induced_pluripotent_stem_cells|induced pluripotent stem cells (iPSC)]].
+** In 2012 a mouse spine was [http://www.ncbi.nlm.nih.gov/pubmed/22223498 repaired] with iPSC. -- So in the year 2032 it should be totally possible to regenerate spinal damages in humans. With that in mind, Bertram Navarre depicts a believable speculation about future's technology.
 ==Related==