LSI

Will the real LSI
please stand up?

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"LSI" has two meanings:

1. In-game, it refers to the "LSI tracker and harness" that Konoko uses to place a beacon on Muro's VTOL in Chapter 5; you did talk to this guy, right? He's the only one who calls it that; the game text refers to it as a Rappelling Harness.
2. "LSI" is also a general engine term for any special item you pick up in a level, which gets added to your inventory and allows the mission to progress. Oni only supports one special item per level and only five missions take advantage of this feature. But from an engine standpoint, they are all termed LSIs. In fact, LSI could be speculated to stand for Level Specific Item.

You can read about each of the game's LSIs starting HERE. You can learn how to give them to the player in a script HERE.